Curriculum Vitae // FILE SJK-2026Postdoctoral Applicant
Jack Sparrow Ph.D.
Computational biologist · single-cell & spatial multi-omics into connectome-scale neuroscience
LocationBoston, MA 02135
Phone(555) 019-2847
Emailjack.sparrow@example.com
WebGoogle Scholar
00 · Profile
objectiveMoving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Research objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
01 · Experience
5 records2025–26
Postdoctoral Researcher
Nakdong University Wonju College of Medicine · Physiology / Cellular Systems Research Center
Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
2023–25
Associate Director
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
Built in-house single-cell & spatial transcriptomics code from scratch; led cross-functional NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program.
2021–23
Manager
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
2019–21
Researcher
Xenotransplantation Research Center, HNU · Seoul
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain/spinal cord) tissue handling.
2020–23
Research Student · MOSAIC
Genomic Medicine Institute, HNU · Multi-Organ Single-cell Atlas of Immune Cells
Contributed the founding proposal; executed within the funded program (500+ donors × 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
02 · Education
3 records2014–23
Ph.D., Biomedical Sciences
Hangang National University · Seoul, Republic of Korea
Mapping Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts. Advisor: Min-Ho Suh, M.D., Ph.D.
2012–14
M.S., Biomedical Sciences
Hangang National University · Seoul
Enhanced LPS-Induced Monocyte Activation by Recombinant Human Soluble CD180.
2008–12
B.S., Genetic Engineering
Suwon Institute of Life Sciences · Suwon
03 · Selected Publications
Sparrow J bold01
Reyes M*, Sparrow J*, Alvarez T*, et al. Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases. Nature Immunology IF 27.7 under review 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
02
Sparrow J*, Tanaka Y*, Truong P*, et al. Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease. Journal of Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
03
Sparrow J*, Delgado J*, Moreau S, et al. Deciphering Dysfunctional Regulatory T Cells in Vitiligo. Allergy IF 12.6 · 2025.
04
Alvarez J*, Sparrow J*, et al. Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys. Xenotransplantation IF 3.9 · 2024.
05
Novak L*, Sparrow J*, et al. Intra-tumoral heterogeneity and immune escape of melanoma arising from chronic UV photodamage by spatial gene expression. JEADV IF 9.2 · 2022.
06
Sparrow J*, et al. mTOR inhibitor-based immunosuppression in allogeneic islet transplantation. Islets IF 2.2 · 2019.
Co-author (selected): eBioMedicine (IF 11.1, 2024) · JEADV (IF 9.2, 2024) · Current Diabetes Reports (IF 4.2, 2021).
04 · Technical Skills
single-cell / spatial / multi-omicscRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, consensus NMF, embedding geometry; custom UMI-aware BAM-level isoform code (Python); Milo, GLIPH, InferCNV; GeoMx DSP; Olink.
machine learning / dl / aiPython (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL (imaging + transcriptomic + clinical); AlphaFold2/3, ProteinMPNN, DiffDock; Linux, R, Git.
experimental10x 5′/3′ scRNA + scTCR libraries; flow cytometry (24 markers); brain/CNS immune profiling; IHC/IF; two-photon; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS & islet models.
05 · Awards & Patents
- Anti-CD25 Humanized Antibody (Patent, No. 1020240091845)2024
- Immunosuppression w/ PI3K Inhibitor (Patent, No. 1020143496217)2019
- Grand Prize, AI Builders Hackathon (Project Nova)2024
- Grand Prize, Metro Innovation Workathon2023
- Best Poster, American Transplant Congress, Chicago2017
- NRF Ph.D. Scholarship · BK21 Plus · HNU Dean's2014–20