Ph.D., Biomedical Sciences2014–23
Hangang National University · Seoul, Korea
Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts · Advisor: Min-Ho Suh, M.D., Ph.D.
Curriculum Vitae · Postdoctoral Applicant
Norman Bates.
Computational single-cell & spatial multi-omics scientist, moving into connectome-scale neuroscience.
18
Total Papers
17
Peer-Reviewed
6
First / Co-First
2
Patents
10+
Years Research
Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Research objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
Education
M.S., Biomedical Sciences2012–14
Hangang National University · Seoul
B.S., Genetic Engineering2008–12
Suwon Institute of Life Sciences · Suwon
Experience
Postdoctoral Researcher2025–26
Nakdong Univ. Wonju College of Medicine · Physiology / Organelle Medicine
Deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
Associate Director, Basic Research2023–25
Meridian Immune Therapeutics Inc. · Seoul
Built in-house single-cell & spatial transcriptomics code from scratch; led NHP (cynomolgus, marmoset) EAE/MS studies; oversaw anti-CD25 antibody regulatory documentation.
Researcher · Xenotransplantation Center, HNU2019–21
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS tissue handling.
Research Student · MOSAIC, HNU2020–23
Founding proposal; funded program of 500+ donors × 6 organs: milestone tracking, multi-site QC, multi-PI coordination.
Selected Publications first / co-first author · * equal contribution
1Reyes M*, Bates N*, Alvarez T*, et al. "Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases." Nature Immunology IF 27.7 · under review 2026. Custom UMI-aware BAM-level analysis (Python); consensus NMF; scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 588 samples, 19 diseases, 214,300 memory CD4⁺ T cells.
2Bates N*, Tanaka Y*, Truong P*, et al. "Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease." Journal of Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
3Bates N*, Delgado J*, Moreau S, et al. "Deciphering Dysfunctional Regulatory T Cells in Vitiligo." Allergy IF 12.6 · 2025.
4Alvarez J*, Bates N*, et al. "Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys." Xenotransplantation IF 3.9 · 2024.
5Novak L*, Bates N*, et al. "Intra-tumoral heterogeneity and immune escape of melanoma from chronic UV photodamage by spatial gene expression profiling." JEADV IF 9.2 · 2022.
6Bates N*, et al. "mTOR inhibitor-based immunosuppression in allogeneic islet transplantation." Islets IF 2.2 · 2019. Co-author, selected: eBioMedicine (2024), JEADV (2024), Current Diabetes Reports (2021).
Technical Skills
Single-cell / spatial / multi-omicscRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, consensus NMF; custom UMI-aware BAM-level isoform code (Python); Milo, GLIPH, InferCNV; GeoMx DSP; Olink proteomics.
Machine learning / DL / AIPython (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL (imaging + transcriptomic + clinical); AlphaFold2/3, ProteinMPNN, DiffDock; Linux, R, Git.
Experimental (domain ground truth)10x 5′/3′ scRNA + scTCR libraries; high-dim flow cytometry (24 markers); brain/CNS immune profiling; IHC/IF; two-photon; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS & islet-transplant models.
Awards & Patents
PatentAnti-CD25 Humanized Antibody2024
PatentImmunosuppression w/ PI3K Inhibitor2019
AwardGrand Prize, AI Builders Hackathon2024
AwardGrand Prize, Metro Innovation Workathon2023
AwardBest Poster, ATC Chicago2017
ScholarNRF Ph.D. · BK21 Plus · HNU Dean's2014–20
References
Min-Ho Suh, M.D., Ph.D.
HNU College of Medicine; CEO/CSO, Meridian Immune. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek, M.D., Ph.D.
HNU, Microbiology & Immunology / IBRI. Computational co-corresponding.
jwbaek@hangang.ac.kr