Ph.D., Biomedical Sciences
Hangang National University · Seoul, Republic of Korea
Mapping Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts · Advisor: Min-Ho Suh, M.D., Ph.D.
2014–2023
ED
Edmond Dantès, Ph.D.
Computational Single-Cell Scientist
220 Harbor Street, Boston, MA 02135◆(555) 019-2847
edmond.dantes@example.com◆edmonddantes.example.com/cv◆Google Scholar
edmond.dantes@example.com◆edmonddantes.example.com/cv◆Google Scholar
Profile
Moving from wet-lab immunology into computational neuroscience, building methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics.
Education
M.S., Biomedical Sciences
Hangang National University · Seoul
Enhanced LPS-Induced Monocyte Activation by Recombinant Human Soluble CD180
2012–2014
B.S., Genetic Engineering
Suwon Institute of Life Sciences · Suwon
2008–2012
Research & Professional Experience
Postdoctoral Researcher
Nakdong University Wonju College of Medicine · Physiology / Cellular Systems Research Center
Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
2025–2026
Associate Director
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
Built in-house single-cell and spatial transcriptomics code from scratch; led cross-functional NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program.
2023–2025
Researcher
Xenotransplantation Research Center, HNU · Seoul
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain/spinal cord) tissue handling.
2019–2021
Research Student, MOSAIC
Multi-Organ Single-cell Atlas of Immune Cells · Genomic Medicine Institute, HNU
Contributed the founding proposal; executed within the funded program (500+ donors × 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
2020–2023
Selected Publications
i.Reyes M*, Dantès E*, Alvarez T*, et al. "Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases." Nature Immunology IF 27.7 under review 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC; ML classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
ii.Dantès E*, Tanaka Y*, Truong P*, et al. "Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease." Journal of Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
iii.Dantès E*, Delgado J*, Moreau S, et al. "Deciphering Dysfunctional Regulatory T Cells in Vitiligo." Allergy IF 12.6 · 2025.
iv.Alvarez J*, Dantès E*, et al. "Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys." Xenotransplantation IF 3.9 · 2024.
v.Novak L*, Dantès E*, et al. "Intra-tumoral heterogeneity and immune escape of melanoma from chronic UV photodamage by spatial gene expression." JEADV IF 9.2 · 2022.
vi.Dantès E*, et al. "mTOR inhibitor-based immunosuppression in allogeneic islet transplantation." Islets IF 2.2 · 2019. Co-author: eBioMedicine (2024), JEADV (2024), Curr. Diabetes Reports (2021).
Technical Skills
Single-cell & spatial
scRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3; CellChat/NicheNet; scVI/scANVI, consensus NMF; custom UMI-aware BAM isoform code (Python); Milo, GLIPH, InferCNV; GeoMx DSP; Olink.
Machine learning & AI
Python (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL (imaging + transcriptomic + clinical); AlphaFold2/3, ProteinMPNN, DiffDock; Linux, R, Git.
Experimental ground truth
10x 5′/3′ scRNA + scTCR libraries; high-dim flow cytometry (24 markers); brain/CNS immune profiling; IHC/IF; two-photon; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS and islet-transplant models.
Awards, Patents & Scholarships
Antagonistic Anti-CD25 Humanized Antibody (Patent)2024
Immunosuppression Comp. w/ PI3K Inhibitor (Patent)2019
Grand Prize, AI Builders Hackathon (Project Nova)2024
Grand Prize, Metro Innovation Workathon2023
Best Poster, American Transplant Congress2017
NRF Ph.D. · BK21 Plus · HNU Dean's Scholarship2014–2020
References
Min-Ho Suh, M.D., Ph.D.
Prof., HNU College of Medicine; CEO/CSO, Meridian Immune. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek, M.D., Ph.D.
Asst. Prof., HNU Microbiology & Immunology / IBRI. Computational co-corresponding.
jwbaek@hangang.ac.krDae-Ho Yoon, Ph.D.
Prof., Physiology, Nakdong Univ. Wonju. Recent research supervisor.
dhyoon@nakdong.ac.krEnglish (native) · Korean (professional working proficiency)