Victor Von Doom, Ph.D.
Computational biologist · single-cell & spatial multi-omics into connectome-scale neuroscience
Boston, MA 02135 · (555) 019-2847 · victor.vondoom@example.com · Google Scholar

Profile

Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Research objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.

Career Timeline

2025–2026
Postdoctoral Researcher
Nakdong University Wonju College of Medicine
2023–2025
Associate Director
Meridian Immune Therapeutics Inc.
2019–2021
Researcher
Xenotransplantation Research Center, HNU
2020–2023
Research Student
MOSAIC · Multi-Organ Single-cell Atlas of Immune Cells, HNU
2014–2023
Ph.D., Biomedical Sciences
Hangang National University
2012–2014
M.S., Biomedical Sciences
Hangang National University
2008–2012
B.S., Genetic Engineering
Suwon Institute of Life Sciences

Selected Publications

01
Reyes M*, Von Doom V*, Alvarez T*, et al. “Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases.” Nature Immunology IF 27.7 · under review 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
02
Von Doom V*, Tanaka Y*, Truong P*, et al. “Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease.” Journal of Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
03
Von Doom V*, Delgado J*, Moreau S, et al. “Deciphering Dysfunctional Regulatory T Cells in Vitiligo.” Allergy IF 12.6 · 2025.
04
Alvarez J*, Von Doom V*, et al. “Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys.” Xenotransplantation IF 3.9 · 2024.

Skills

scRNA-seqscTCR-seqsnATACSeuratScanpyscVI/scANVIconsensus NMFPyTorchXGBoostGNNmultimodal DLAlphaFoldGeoMx DSPOlinkPythonRGit

References

Min-Ho Suh, M.D., Ph.D.
HNU College of Medicine; CEO/CSO, Meridian Immune. Ph.D. advisor.
mhsuh@hangang.ac.kr
Ji-Won Baek, M.D., Ph.D.
HNU, Microbiology & Immunology / IBRI. Computational co-corresponding.
jwbaek@hangang.ac.kr
Dae-Ho Yoon, Ph.D.
Nakdong Wonju, Physiology. Recent research supervisor.
dhyoon@nakdong.ac.kr