SYS//CV_LOAD ▸ OK · PROFILE.SJK · REV 2026.07
STATUS: OPEN TO POSTDOC
DIANA PRINCE, Ph.D.
Computational biologist moving from single-cell and spatial multi-omics into connectome-scale neuroscience.
Boston, MA 02135(555) 019-2847diana.prince@example.comdianaprince.example.com/cv
Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
Experience Log
| 01 | Postdoctoral Researcher Nakdong University Wonju College of Medicine · Physiology / Cellular Systems Research Center Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models. |
2025–2026 |
| 02 | Associate Director Meridian Immune Therapeutics Inc. · Basic Research, Seoul Built in-house single-cell and spatial transcriptomics code from scratch; led NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program. |
2023–2025 |
| 03 | Researcher Xenotransplantation Research Center, HNU · Seoul Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain/spinal cord) tissue handling. |
2019–2021 |
| 04 | Research Student · MOSAIC Multi-Organ Single-cell Atlas of Immune Cells, HNU · Genomic Medicine Institute Contributed the founding proposal; executed within the funded program (500+ donors, 6 organs): milestone tracking, multi-site QC, multi-PI coordination. |
2020–2023 |
Education
| Ph.D | Biomedical Sciences · Hangang National University Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts. Advisor: Min-Ho Suh, M.D., Ph.D. | 2014–2023 |
| M.S | Biomedical Sciences · Hangang National University | 2012–2014 |
| B.S | Genetic Engineering · Suwon Institute of Life Sciences | 2008–2012 |
Publications
18
Total
17
Peer-reviewed
06
First / co-first
01
Under review
01Reyes M*, Prince D*, Alvarez T*, et al. "Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases." Nature Immunology IF 27.7 UNDER REVIEW 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC; classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
02Prince D*, Tanaka Y*, Truong P*, et al. "Immune cell-enriched scRNA-seq: infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease." Journal of Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
03Prince D*, Delgado J*, Moreau S, et al. "Deciphering Dysfunctional Regulatory T Cells in Vitiligo." Allergy IF 12.6 · 2025.
04Alvarez J*, Prince D*, et al. "Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys." Xenotransplantation IF 3.9 · 2024.
05Novak L*, Prince D*, et al. "Intra-tumoral heterogeneity and immune escape of melanoma from chronic UV photodamage by spatial gene expression." JEADV IF 9.2 · 2022.
06Prince D*, et al. "mTOR inhibitor-based immunosuppression in allogeneic islet transplantation." Islets IF 2.2 · 2019. Co-author: eBioMedicine (2024), JEADV (2024), Curr. Diabetes Reports (2021).
Skill Stack
Single-cell / spatial / multi-omicscRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, batch integration, consensus NMF; custom UMI-aware BAM-level isoform code (Python); Milo, GLIPH, InferCNV, weighted-LMM; GeoMx DSP; Olink proteomics.
ML / DL / AIPython (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL (imaging + transcriptomic + clinical); vision-language transformers; AlphaFold2/3, ProteinMPNN, DiffDock, MolFormer; Linux, R, Git.
Experimental ground truth10x 5′/3′ scRNA + scTCR libraries; 24-marker flow, 6-way FACS; brain/CNS immune profiling; IHC/IF (frozen & FFPE); two-photon; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS and islet models.
Awards / Patents
Anti-CD25 Humanized Ab (Patent)2024
PI3K Inhibitor Composition (Patent)2019
Grand Prize, AI Builders Hackathon2024
Grand Prize, Metro Innovation Workathon2023
Best Poster, ATC Chicago2017
NRF Ph.D. · BK21 Plus · Dean's2014–20
References
Min-Ho Suh, M.D., Ph.D.
HNU; CEO/CSO, Meridian Immune. Ph.D. advisor. mhsuh@hangang.ac.kr
Ji-Won Baek, M.D., Ph.D.
HNU, Microbiology & Immunology / IBRI. Computational co-corresponding. jwbaek@hangang.ac.kr
Dae-Ho Yoon, Ph.D.
Nakdong Wonju, Physiology. Recent supervisor. dhyoon@nakdong.ac.kr