Ph.D., Biomedical Sciences 2014–2023
Hangang National University · Seoul, Republic of Korea
Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts · Advisor: Min-Ho Suh, M.D., Ph.D.
Curriculum Vitae · 2026
Saul Goodman, Ph.D.
Computational biologist moving from single-cell and spatial multi-omics into connectome-scale neuroscience.
Boston, MA 02135
(555) 019-2847
saul.goodman@example.com
Google Scholar
Publication record
18total papers
17peer-reviewed
6first / co-first
Profile
I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Objective: connect molecular cell identity to circuit structure by integrating connectomics with transcriptomics.
Education
M.S., Biomedical Sciences 2012–2014
Hangang National University · Seoul
Enhanced LPS-Induced Monocyte Activation by Recombinant Human Soluble CD180
B.S., Genetic Engineering 2008–2012
Suwon Institute of Life Sciences · Suwon
Research interests
- Inferring cellular identity from incomplete, high-dimensional data
- Multi-modal integration linking molecular identity to structure
- Cell-type-specific interaction and connectivity statistics
- Atlas-scale, structure-to-function modeling across species
Experience
Postdoctoral Researcher 2025–2026
Nakdong University Wonju College of Medicine · Physiology / Cellular Systems Research Center
Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
Associate Director 2023–2025
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
Built in-house single-cell and spatial transcriptomics analysis code from scratch; led NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program.
Researcher 2019–2021
Xenotransplantation Research Center, HNU · Seoul
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain/spinal cord) tissue handling.
Research Student 2020–2023
MOSAIC, Multi-Organ Single-cell Atlas of Immune Cells, HNU · Genomic Medicine Institute
Contributed the founding proposal; executed within the funded program (500+ donors × 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
Selected Publications
1Reyes M*, Goodman S*, Alvarez T*, et al. "Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases." Nature Immunology IF 27.7 · under review, 2026. scRNA + scTCR + snATAC integration; classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
2Goodman S*, Tanaka Y*, Truong P*, et al. "Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease." Journal of Neuroimmunology IF 2.9 · 2025.
3Goodman S*, Delgado J*, Moreau S, et al. "Deciphering Dysfunctional Regulatory T Cells in Vitiligo." Allergy IF 12.6 · 2025.
4Alvarez J*, Goodman S*, et al. "Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys." Xenotransplantation IF 3.9 · 2024.
5Novak L*, Goodman S*, et al. "Intra-tumoral heterogeneity and immune escape of melanoma from chronic UV photodamage by spatial gene expression." JEADV IF 9.2 · 2022.
6Goodman S*, et al. "mTOR inhibitor-based immunosuppression in allogeneic islet transplantation." Islets IF 2.2 · 2019. Co-author: eBioMedicine (2024), JEADV (2024), Curr. Diabetes Reports (2021).
Patents
Antagonistic Anti-CD25 Humanized Antibody2024
Immunosuppression Composition w/ PI3K Inhibitor2019
Patent No. 1020240091845 · 1020143496217.
Skills
Single-cell / spatialSeurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, consensus NMF; UMI-aware BAM isoform code; Milo, GLIPH, InferCNV; GeoMx, Olink.
ML / DL / AIPython (scikit-learn, XGBoost, PyTorch); VAE/GAN/GNN; multimodal DL; AlphaFold2/3, ProteinMPNN, DiffDock; Linux, R, Git.
Experimental10x scRNA + scTCR; flow (24 markers); CNS immune profiling; IHC/IF; two-photon; NHP CNS tissue.
Awards & Scholarships
Grand Prize, AI Builders Hackathon2024
Grand Prize, Metro Innovation Workathon2023
Best Poster, Am. Transplant Congress2017
Best Presentation, KAI2017
NRF Ph.D. · BK21 Plus Scholarship2014–20
HNU Dean's Lecture & Research2014–20
References
Min-Ho Suh, M.D., Ph.D.
HNU College of Medicine; CEO/CSO, Meridian Immune. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek, M.D., Ph.D.
HNU, Microbiology & Immunology / IBRI. Computational co-corresponding.
jwbaek@hangang.ac.kr