Ph.D., Biomedical Sciences · 2014–2023
Hangang National University · Seoul, Republic of Korea
Mapping Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts · Advisor: Min-Ho Suh, M.D., Ph.D.
Curriculum Vitae
Jesse Pinkman, Ph.D.
Computational biologist moving from single-cell and spatial multi-omics into connectome-scale neuroscience.
220 Harbor Street, Boston, MA 02135
(555) 019-2847
jesse.pinkman@example.com
Google Scholar
Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Objective: connect molecular cell identity to circuit structure by integrating connectomics with transcriptomics.
Skills
Single-cell / spatial / multi-omicscRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, consensus NMF; custom UMI-aware BAM-level isoform code (Python); Milo, GLIPH, InferCNV; GeoMx DSP; Olink.
Machine learning / DL / AIPython (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL (imaging + transcriptomic + clinical); AlphaFold2/3, ProteinMPNN, DiffDock; Linux, R, Git.
Experimental10x 5′/3′ scRNA + scTCR; flow cytometry (24 markers); brain/CNS immune profiling; IHC/IF; two-photon; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS and islet models.
Awards & Patents
- Anti-CD25 Humanized Antibody (Patent)2024
- Immunosuppression w/ PI3K Inhibitor (Patent)2019
- Grand Prize, AI Builders Hackathon2024
- Grand Prize, Metro Innovation Workathon2023
- Best Poster, American Transplant Congress2017
- NRF Ph.D. · BK21 Plus · HNU Dean's2014–20
References
Min-Ho Suh, M.D., Ph.D.
HNU College of Medicine; CEO/CSO, Meridian Immune. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek, M.D., Ph.D.
HNU, Microbiology & Immunology / IBRI. Computational co-corresponding.
jwbaek@hangang.ac.krEducation
M.S., Biomedical Sciences · 2012–2014
Hangang National University · Seoul
Enhanced LPS-Induced Monocyte Activation by Recombinant Human Soluble CD180
B.S., Genetic Engineering · 2008–2012
Suwon Institute of Life Sciences · Suwon
Experience
Postdoctoral Researcher · 2025–2026
Nakdong University Wonju College of Medicine · Physiology / Cellular Systems Research Center
Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
Associate Director · 2023–2025
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
Built in-house single-cell and spatial transcriptomics analysis code from scratch; led NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program.
Researcher · 2019–2021
Xenotransplantation Research Center, HNU · Seoul
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain/spinal cord) tissue handling.
Research Student · 2020–2023
MOSAIC, Multi-Organ Single-cell Atlas of Immune Cells, HNU · Genomic Medicine Institute
Contributed the founding proposal; executed within the funded program (500+ donors × 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
Selected Publications
1Reyes M*, Pinkman J*, Alvarez T*, et al. "Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases." Nature Immunology, IF 27.7 · under review, 2026. scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
2Pinkman J*, Tanaka Y*, Truong P*, et al. "Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease." Journal of Neuroimmunology, IF 2.9 · 2025. 11,587 cells, 10 populations.
3Pinkman J*, Delgado J*, Moreau S, et al. "Deciphering Dysfunctional Regulatory T Cells in Vitiligo." Allergy, IF 12.6 · 2025.
4Alvarez J*, Pinkman J*, et al. "Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys." Xenotransplantation, IF 3.9 · 2024.
5Novak L*, Pinkman J*, et al. "Intra-tumoral heterogeneity and immune escape of melanoma from chronic UV photodamage by spatial gene expression." JEADV, IF 9.2 · 2022.
6Pinkman J*, et al. "mTOR inhibitor-based immunosuppression in allogeneic islet transplantation." Islets, IF 2.2 · 2019. Co-author: eBioMedicine (2024), JEADV (2024), Curr. Diabetes Reports (2021).