/cv/seong-jun-kang.html
제인 도 · Ph.D.
● 2026
Hermione Granger
Computational biologist moving from single-cell and spatial multi-omics into connectome-scale neuroscience.
220 Harbor Street, Boston MA
(555) 019-2847
hermione.granger@example.com
Google Scholar
hermionegranger.example.com
Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Research objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
Education
2014–2023
Ph.D., Biomedical Sciences
Hangang National University · Seoul, Republic of Korea
Thesis: Mapping Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts. Advisor: Min-Ho Suh, M.D., Ph.D.
2012–2014
M.S., Biomedical Sciences
Hangang National University · Seoul
Thesis: Enhanced LPS-Induced Monocyte Activation by Recombinant Human Soluble CD180.
2008–2012
B.S., Genetic Engineering
Suwon Institute of Life Sciences · Suwon
Experience
2025–2026
Postdoctoral Researcher
Nakdong University Wonju College of Medicine · Physiology / Cellular Systems Research Center
Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
2023–2025
Associate Director, Basic Research
Meridian Immune Therapeutics Inc. · Seoul
Built in-house single-cell and spatial transcriptomics code from scratch; led cross-functional NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program.
2021–2023
Manager, Basic Research
Meridian Immune Therapeutics Inc. · Seoul
2019–2021
Researcher
Xenotransplantation Research Center, HNU · Seoul
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain/spinal cord) tissue handling.
2020–2023
Research Student, MOSAIC
Multi-Organ Single-cell Atlas of Immune Cells, HNU · Genomic Medicine Institute
Contributed the founding proposal; executed within the funded program (500+ donors x 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
Selected Publications
01
Reyes M*, Granger H*, Alvarez T*, et al. Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases. Nature Immunology IF 27.7 under review 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 702 samples, 251,055 CD4 T cells.
02
Granger H*, Tanaka Y*, Truong P*, et al. Immune cell-enriched scRNA-seq unveils infiltrated CD8 T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease. J. Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
03
Granger H*, Delgado J*, Moreau S, et al. Deciphering Dysfunctional Regulatory T Cells in Vitiligo. Allergy IF 12.6 · 2025.
04
Alvarez J*, Granger H*, et al. Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in diabetic rhesus monkeys. Xenotransplantation IF 3.9 · 2024.
05
Novak L*, Granger H*, et al. Intra-tumoral heterogeneity and immune escape of melanoma arising from chronic UV photodamage revealed by spatial gene expression profiling. JEADV IF 9.2 · 2022.
06
Granger H*, et al. mTOR inhibitor-based immunosuppression in allogeneic islet transplantation. Islets IF 2.2 · 2019. Co-author: eBioMedicine (2024), JEADV (2024), Current Diabetes Reports (2021).
Technical Skills
Single-cell / Spatial / Multi-omic
scRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, batch integration, consensus NMF; custom UMI-aware BAM-level isoform code (Python); Milo KNN-graph DA, GLIPH, InferCNV; GeoMx DSP; Olink proteomics.
ML / DL / AI
Python (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL integration (imaging + transcriptomic + clinical); vision-language transformers; AlphaFold2/3, ProteinMPNN, DiffDock, MolFormer; Linux servers, R/RStudio, Git.
Experimental
10x 5'/3' scRNA + scTCR library generation; high-dimensional flow cytometry (24 markers), 10-color FACS; brain/CNS immune profiling (perfusion, digestion, Percoll, CD45 FACS); IHC/IF; two-photon microscopy; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS and islet-transplant models.
Awards, Patents & Scholarships
Antagonistic Anti-CD25 Humanized Antibody (Patent No. 1020240091845)2024
Immunosuppression Composition Comprising PI3K Inhibitor (Patent)2019
Grand Prize, 2024 AI Builders Hackathon (Project Nova Team)2024
Grand Prize, Metro Innovation Workathon (Work Process Innovation)2023
Best Poster Award, American Transplant Congress, Chicago2017
NRF Ph.D. Scholarship · BK21 Plus · HNU Dean's Lecture & Research Support2014–2020
References
Min-Ho Suh, M.D., Ph.D.
Professor, HNU College of Medicine; CEO/CSO, Meridian Immune Therapeutics. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek, M.D., Ph.D.
Assistant Professor, Microbiology & Immunology / IBRI, HNU. Computational co-corresponding.
jwbaek@hangang.ac.krDae-Ho Yoon, Ph.D.
Professor, Physiology, Nakdong University Wonju College of Medicine. Recent research supervisor.
dhyoon@nakdong.ac.krHermione Granger · Curriculum VitaeKorean (native) · English (professional working)