SR
Steve Rogers, Ph.D.
Computational biologist, single-cell and spatial multi-omics into connectome-scale neuroscience
Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. My objective is to connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
Core Proficiencies
Python (Scanpy, PyTorch, scikit-learn)expert
R (Seurat, Bioconductor)advanced
Spatial (Squidpy, GeoMx DSP, CellChat)advanced
Deep learning (VAE/GAN/GNN, multimodal)advanced
Flow cytometry & CNS immune profilingexpert
Experience
Postdoctoral Researcher2025–2026
Nakdong Univ. Wonju College of Medicine · Physiology / Organelle Medicine RC
Deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
Associate Director2023–2025
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
Built in-house single-cell and spatial transcriptomics code from scratch; led NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw anti-CD25 humanized-antibody regulatory documentation.
Researcher2019–2021
Xenotransplantation Research Center, HNU · Seoul
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS tissue handling.
Research Student, MOSAIC2020–2023
Multi-Organ Single-cell Atlas of Immune Cells, HNU · Genomic Medicine Institute
Founding proposal; funded program (500+ donors, 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
Education
Ph.D., Biomedical Sciences2014–23
Hangang National University
Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts. Advisor: Min-Ho Suh.
M.S., Biomedical Sciences2012–14
Hangang National University
B.S., Genetic Engineering2008–12
Suwon Institute of Life Sciences · Suwon
Selected Publications, first / co-first highlighted
1Reyes M*, Rogers S*, Alvarez T*, et al. "Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases." Nature Immunology IF 27.7 · under review 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC integration; classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
2Rogers S*, Tanaka Y*, Truong P*, et al. "Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease." J. Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
3Rogers S*, Delgado J*, Moreau S, et al. "Deciphering Dysfunctional Regulatory T Cells in Vitiligo." Allergy IF 12.6 · 2025.
4Alvarez J*, Rogers S*, et al. "Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys." Xenotransplantation IF 3.9 · 2024.
5Novak L*, Rogers S*, et al. "Intra-tumoral heterogeneity and immune escape of melanoma from chronic UV photodamage by spatial gene expression." JEADV IF 9.2 · 2022.
6Rogers S*, et al. "mTOR inhibitor-based immunosuppression in allogeneic islet transplantation." Islets IF 2.2 · 2019. Co-author: eBioMedicine (2024), JEADV (2024), Curr. Diabetes Reports (2021).
Awards & Patents
Anti-CD25 Humanized Antibody, Patent2024
PI3K Inhibitor Immunosuppression, Patent2019
Grand Prize, AI Builders Hackathon2024
Grand Prize, Metro Innovation Workathon2023
Best Poster, ATC Chicago2017
NRF · BK21 Plus · HNU Dean's2014–20
Skills Detail
scRNA/scTCR/snATAC, scVI/scANVI, consensus NMF, Milo, GLIPH, InferCNV, Olink. XGBoost/LightGBM/CatBoost, vision-language transformers, AlphaFold2/3, ProteinMPNN, DiffDock. 10x 5′/3′ libraries, 24-marker flow, two-photon, IHC/IF, NHP CNS tissue. Korean (native), English (professional working).