Ted Mosby, Ph.D.
Computational biologist, single-cell & spatial multi-omics moving into connectome-scale neuroscience
220 Harbor Street, Boston, MA 02135|
(555) 019-2847|
ted.mosby@example.com|
Google Scholar|
tedmosby.example.com/cv
Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Research objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
Education
Ph.D., Biomedical Sciences2014–2023
Hangang National University · Seoul, Republic of Korea
Thesis: Mapping Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts. Advisor: Min-Ho Suh, M.D., Ph.D.
M.S., Biomedical Sciences2012–2014
Hangang National University · Seoul
Thesis: Enhanced LPS-Induced Monocyte Activation by Recombinant Human Soluble CD180. Advisor: Min-Ho Suh, M.D., Ph.D.
B.S., Genetic Engineering2008–2012
Suwon Institute of Life Sciences · Suwon
Research & Professional Experience
Postdoctoral Researcher2025–2026
Nakdong University Wonju College of Medicine · Physiology / Cellular Systems Research Center
Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
Associate Director2023–2025
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
Built in-house single-cell & spatial transcriptomics analysis code from scratch; led cross-functional NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program.
Researcher2019–2021
Xenotransplantation Research Center, HNU · Seoul
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain/spinal cord) tissue handling.
Research Student, MOSAIC2020–2023
Multi-Organ Single-cell Atlas of Immune Cells, HNU · Genomic Medicine Institute
Contributed the founding proposal; executed within the funded program (500+ donors × 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
Selected Publications
1Reyes M*, Mosby T*, Alvarez T*, et al. Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases. Nature Immunology IF 27.7 · under review, 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
2Mosby T*, Tanaka Y*, Truong P*, et al. Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease. Journal of Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
3Mosby T*, Delgado J*, Moreau S, et al. Deciphering Dysfunctional Regulatory T Cells in Vitiligo. Allergy IF 12.6 · 2025.
4Alvarez J*, Mosby T*, et al. Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys. Xenotransplantation IF 3.9 · 2024.
5Novak L*, Mosby T*, et al. Intra-tumoral heterogeneity and immune escape of melanoma arising from chronic UV photodamage by spatial gene expression. JEADV IF 9.2 · 2022.
6Mosby T*, et al. mTOR inhibitor-based immunosuppression in allogeneic islet transplantation. Islets IF 2.2 · 2019. Co-author, selected: eBioMedicine (IF 11.1, 2024), JEADV (2024), Current Diabetes Reports (2021).
Technical Skills
Single-cell / spatial / multi-omic: scRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, batch integration, consensus NMF; custom UMI-aware BAM-level isoform code (Python); Milo, GLIPH, InferCNV; GeoMx DSP; Olink proteomics.
Machine learning / DL / AI: Python (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL (imaging + transcriptomic + clinical); AlphaFold2/3, ProteinMPNN, DiffDock, MolFormer; Linux, R/RStudio, Git.
Experimental: 10x 5′/3′ scRNA + scTCR libraries; high-dim flow cytometry (24 markers), 10-color FACS; brain/CNS immune profiling; IHC/IF (frozen & FFPE); two-photon; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS & islet-transplant models.
Awards, Patents & Scholarships
Antagonistic Anti-CD25 Humanized Antibody, Patent No. 10202400918452024
Immunosuppression Composition Comprising PI3K Inhibitor, Patent No. 10201434962172019
Grand Prize, 2024 AI Builders Hackathon (Project Nova Team)2024
Grand Prize, Metro Innovation Workathon (Work Process Innovation)2023
Best Poster, American Transplant Congress, Chicago · Best Presentation, KAI2017
NRF Ph.D. Scholarship · BK21 Plus · HNU Dean's Lecture & Research Support2014–2020
References
Min-Ho Suh, M.D., Ph.D.
HNU College of Medicine; CEO/CSO, Meridian Immune Therapeutics. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek, M.D., Ph.D.
HNU, Microbiology & Immunology / IBRI. Co-corresponding, computational / single-cell.
jwbaek@hangang.ac.krDae-Ho Yoon, Ph.D.
Nakdong Wonju, Physiology & Global Medical Science. Most recent research supervisor.
dhyoon@nakdong.ac.kr