Frodo Baggins, Ph.D.
Computational biologist · single-cell & spatial multi-omics into connectome-scale neuroscience
Boston, MA 02135 · (555) 019-2847 · frodo.baggins@example.com · Google Scholar
Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Research objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
Career & Education Timeline
2025–2026
Postdoctoral Researcher
Nakdong University Wonju College of Medicine
2023–2025
Associate Director
Meridian Immune Therapeutics Inc.
2019–2021
Researcher
Xenotransplantation Research Center, HNU
2020–2023
Research Student
MOSAIC · Multi-Organ Single-cell Atlas of Immune Cells, HNU
2014–2023
Ph.D., Biomedical Sciences
Hangang National University
2012–2014
M.S., Biomedical Sciences
Hangang National University
2008–2012
B.S., Genetic Engineering
Suwon Institute of Life Sciences
Selected Publications
01
Reyes M*, Baggins F*, Alvarez T*, et al. “Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases.” Nature Immunology IF 27.7 · under review 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
02
Baggins F*, Tanaka Y*, Truong P*, et al. “Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease.” Journal of Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
03
Baggins F*, Delgado J*, Moreau S, et al. “Deciphering Dysfunctional Regulatory T Cells in Vitiligo.” Allergy IF 12.6 · 2025.
04
Alvarez J*, Baggins F*, et al. “Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys.” Xenotransplantation IF 3.9 · 2024.
Skills
Awards, Patents & Scholarships
Antagonistic Anti-CD25 Humanized Antibody (Patent)2024
Immunosuppression Composition w/ PI3K Inhibitor (Patent)2019
Grand Prize, AI Builders Hackathon (Project Nova)2024
Grand Prize, Metro Innovation Workathon2023
Best Poster, American Transplant Congress (Chicago)2017
NRF Ph.D. Scholarship · BK21 Plus · HNU Dean's2014–2020
References
Min-Ho Suh, M.D., Ph.D.
HNU College of Medicine; CEO/CSO, Meridian Immune. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek, M.D., Ph.D.
HNU, Microbiology & Immunology / IBRI. Computational co-corresponding.
jwbaek@hangang.ac.kr