Doctor of Philosophy, Biomedical Sciences
Hangang National University · Seoul, Republic of Korea
2014–2023
Thesis: Mapping Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts. Advisor: Min-Ho Suh, M.D., Ph.D.
Seong‑Jun Danvers,
Doctor of Philosophy
Computational biologist moving from single-cell and spatial multi-omics into connectome-scale neuroscience.
220 Harbor Street, Boston, MA·(555) 019-2847·carol.danvers@example.com
Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Research objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
Education
Master of Science, Biomedical Sciences
Hangang National University · Seoul
2012–2014
Thesis: Enhanced LPS-Induced Monocyte Activation by Recombinant Human Soluble CD180.
Bachelor of Science, Genetic Engineering
Suwon Institute of Life Sciences · Suwon
2008–2012
Experience
Postdoctoral Researcher
Nakdong University Wonju College of Medicine · Physiology / Cellular Systems Research Center
2025–2026
Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
Associate Director
Meridian Immune Therapeutics Inc. · Department of Basic Research, Seoul
2023–2025
Built in-house single-cell and spatial transcriptomics analysis code from scratch; led cross-functional NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program.
Researcher
Xenotransplantation Research Center, HNU · Seoul
2019–2021
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain and spinal cord) tissue handling.
Research Student, MOSAIC
Multi-Organ Single-cell Atlas of Immune Cells, Genomic Medicine Institute, HNU · Seoul
2020–2023
Contributed the founding proposal; executed within the funded program (500+ donors, 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
Selected Publications
IReyes M*, Danvers C*, Alvarez T*, et al. "Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases." Nature Immunology IF 27.7 · under review, 2026. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
IIDanvers C*, Tanaka Y*, Truong P*, et al. "Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease." Journal of Neuroimmunology IF 2.9 · 2025. 9,240 cells, 8 immune populations.
IIIDanvers C*, Delgado J*, Moreau S, et al. "Deciphering Dysfunctional Regulatory T Cells in Vitiligo." Allergy IF 12.6 · 2025.
IVAlvarez J*, Danvers C*, et al. "Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys." Xenotransplantation IF 3.9 · 2024.
VNovak L*, Danvers C*, et al. "Intra-tumoral heterogeneity and immune escape of melanoma from chronic UV photodamage by spatial gene expression." JEADV IF 9.2 · 2022.
VIDanvers C*, et al. "mTOR inhibitor-based immunosuppression in allogeneic islet transplantation." Islets IF 2.2 · 2019.
Co-author (selected): eBioMedicine (IF 11.1, 2024), JEADV (IF 9.2, 2024), Current Diabetes Reports (IF 4.2, 2021).
Technical Skills
Single-cell, spatial & multi-omicscRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, consensus NMF, embedding geometry; custom UMI-aware BAM-level isoform code (Python); Milo, GLIPH, InferCNV; GeoMx DSP; Olink proteomics.
Machine Learning, Deep Learning & AIPython (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL (imaging + transcriptomic + clinical); AlphaFold2/3, ProteinMPNN, DiffDock, MolFormer; Linux, R, Git.
Experimental Ground Truth10x 5′/3′ scRNA + scTCR libraries; high-dimensional flow cytometry (24 markers); brain/CNS immune profiling; IHC/IF; two-photon; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS and islet-transplant models.
Awards & Patents
Antagonistic Anti-CD25 Humanized Antibody, Patent No. 10202400918452024
Immunosuppression Composition Comprising PI3K Inhibitor, Patent2019
Grand Prize, 2024 AI Builders Hackathon (Project Nova)2024
Grand Prize, Metro Innovation Workathon2023
Best Poster, American Transplant Congress, Chicago2017
NRF Ph.D. Scholarship · BK21 Plus · HNU Dean's Scholarship2014–2020
References
Min-Ho Suh
M.D., Ph.D. Professor, HNU College of Medicine; CEO/CSO, Meridian Immune. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek
M.D., Ph.D. Assistant Professor, HNU Microbiology & Immunology / IBRI. Co-corresponding.
jwbaek@hangang.ac.krDae-Ho Yoon
Ph.D. Professor, Physiology, Nakdong Wonju. Most recent research supervisor.
dhyoon@nakdong.ac.kr