Ph.D., Biomedical Sciences
Hangang National University · Seoul, Republic of Korea
Thesis: Mapping Dendritic Cell Heterogeneity Across Chronic Inflammatory Contexts. Advisor: Min-Ho Suh, M.D., Ph.D.
Rachel Green, Ph.D.
Curriculum Vitae
Index · Boston, MA
제인 도
Index · Boston, MA
제인 도
Computational biologist moving from single-cell and spatial multi-omics into connectome-scale neuroscience
220 Harbor Street, Boston, MA 02135/
(555) 019-2847/
rachel.green@example.com/
rachelgreen.example.com/cv/
Google Scholar
00 Profile
Moving from wet-lab immunology into computational neuroscience. I build methods that infer cellular identity, state, and interaction from large, incomplete single-cell and spatial data. Research objective: connect molecular cell identity to circuit structure and function by integrating connectomics with transcriptomics, growing into connectome-constrained circuit models.
Interestssingle-cell & spatial multi-omics · cell-type inference from incomplete data · self-supervised / embedding representation learning · connectome × transcriptomics · computational neuroimmunology · reproducible ML/DL analysis
01 Education
2014–2023
2012–2014
M.S., Biomedical Sciences
Hangang National University · Seoul
Thesis: Enhanced LPS-Induced Monocyte Activation by Recombinant Human Soluble CD180.
2008–2012
B.S., Genetic Engineering
Suwon Institute of Life Sciences · Suwon
02 Research & Experience
2025–2026
Postdoctoral Researcher
Nakdong Univ. Wonju College of Medicine · Physiology / Cellular Systems Research Center
Developed deep-learning multimodal-integration models fusing imaging, transcriptomic, and clinical data into single predictive models.
2023–2025
Associate Director
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
Built in-house single-cell and spatial transcriptomics analysis code from scratch; led cross-functional NHP (cynomolgus, marmoset) EAE/MS multi-omic studies; oversaw regulatory documentation for an anti-CD25 humanized-antibody program.
2021–2023
Manager
Meridian Immune Therapeutics Inc. · Basic Research, Seoul
2019–2021
Researcher
Xenotransplantation Research Center, HNU · Seoul
Rhesus macaque tissue processing, longitudinal immune monitoring, CNS (brain/spinal cord) tissue handling.
2020–2023
Research Student · MOSAIC
Multi-Organ Single-cell Atlas of Immune Cells, Genomic Medicine Institute, HNU
Contributed the founding proposal; executed within the funded program (500+ donors × 6 organs): milestone tracking, multi-site QC, multi-PI coordination.
2014–2016
Teaching Assistant
HNU College of Medicine · Microbiology and Immunology
03 Selected Publications
2026IF 27.7
Reyes M*, Green R*, Alvarez T*, et al. "Conserved PDE9X short-isoform bias defines pathogenic Th1.17 state across human inflammatory diseases." Nature Immunology · under review. UMI-aware BAM-level isoform analysis; scRNA + scTCR + snATAC integration; ML classifier AUC 0.812; 702 samples, 251,055 CD4⁺ T cells.
2025IF 2.9
Green R*, Tanaka Y*, Truong P*, et al. "Immune cell-enriched scRNA-seq unveils infiltrated CD8⁺ T resident memory cells and meningeal lymphatic endothelium in Parkinson's disease." Journal of Neuroimmunology. 9,240 cells, 8 immune populations.
2025IF 12.6
Green R*, Delgado J*, Moreau S, et al. "Deciphering Dysfunctional Regulatory T Cells in Vitiligo." Allergy.
2024IF 3.9
Alvarez J*, Green R*, et al. "Long-term control of diabetes by a baricitinib-based regimen after allo-islet transplantation in rhesus monkeys." Xenotransplantation.
2022IF 9.2
Novak L*, Green R*, et al. "Intra-tumoral heterogeneity and immune escape of melanoma from chronic UV photodamage by spatial gene expression." JEADV.
2019IF 2.2
Green R*, et al. "mTOR inhibitor-based immunosuppression in allogeneic islet transplantation." Islets.
Co-author (selected): eBioMedicine (IF 11.1, 2024) · JEADV (IF 9.2, 2024) · Current Diabetes Reports (IF 4.2, 2021). *Co-first = equal contribution (shared first authorship).
04 Technical Skills
Single-cell / spatial
scRNA-seq, scTCR-seq, snRNA/snATAC; Seurat, Scanpy, Squidpy, Monocle3, CellChat/NicheNet; scVI/scANVI, batch integration, consensus NMF; custom UMI-aware BAM-level isoform code (Python); Milo, GLIPH, InferCNV; GeoMx DSP; Olink proteomics.
ML / DL / AI
Python (scikit-learn, XGBoost/LightGBM/CatBoost, PyTorch); AUC-validated classifiers; VAE/GAN/GNN; multimodal DL integration (imaging + transcriptomic + clinical); AlphaFold2/3, ProteinMPNN, DiffDock, MolFormer; Linux, R, Git.
Experimental
10x 5′/3′ scRNA + scTCR libraries; high-dimensional flow cytometry (24 markers); brain/CNS immune profiling; IHC/IF (frozen & FFPE); two-photon microscopy; NHP CNS tissue (rhesus, cynomolgus, marmoset); EAE/MS & islet-transplant models.
05 Awards, Patents & Scholarships
2024
PatentAntagonistic Anti-CD25 Humanized Antibody (No. 1020240091845)
2019
PatentImmunosuppression Composition Comprising PI3K Inhibitor (No. 1020143496217)
2024
AwardGrand Prize, 2024 AI Builders Hackathon (Project Nova Team)
2023
AwardGrand Prize, Metro Innovation Workathon (Work Process Innovation)
2017
AwardBest Poster, American Transplant Congress · Best Presentation, Korean Assoc. of Immunologists
2014–2020
Schol.NRF Ph.D. Research · HNU Dean's Lecture & Research · BK21 Plus
06 References
Min-Ho Suh, M.D., Ph.D.
HNU College of Medicine; CEO/CSO, Meridian Immune. Ph.D. advisor.
mhsuh@hangang.ac.krJi-Won Baek, M.D., Ph.D.
HNU, Microbiology & Immunology / IBRI. Computational co-corresponding.
jwbaek@hangang.ac.kr